Abstract

The effects of polyphenolic impurities on the biological activity of fucoidan samples from the brown alga Fucus distichus subsp. evanescens were studied using the model of developing embryos of the sea urchin Strongylocentrotus intermedius. The embryotoxic action of fucophloretol from F. evanescens (IC₅₀ = 96.90 ± 12.20 μmol/L) and cucumarioside A₇ (a triterpene glycoside) from Cucumaria frondosa subsp. japonica (IC₅₀ = 0.39 ± 0.01 μmol/L) was assessed. The ability of fucoidans with different levels of polyphenolic impurities to partially or completely reduce the embryotoxic action of cucumarioside A₇ from C. japonica has been shown.

中文翻译：

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来自褐藻 Fucus distichus subsp. 的褐藻糖胶样品中多酚杂质的影响。evanescens (C. Agardh) HT Powell，1957 年关于海胆 Strongylocentrotus intermedius 的胚胎发生（A. Agassiz，1864 年）和黄瓜苷的胚胎毒性作用

摘要

多酚杂质对褐藻Fucus distichus subsp.岩藻依聚糖样品生物活性的影响。使用海胆Strongylocentrotus intermedius 的胚胎发育模型对evanescens进行了研究。来自F. evanescens的岩藻绿醇(IC ₅₀ = 96.90 ± 12.20 μmol/L) 和来自Cucumaria frondosa subsp 的cucumarioside A ₇（一种三萜糖苷）的胚胎毒性作用。粳稻(IC ₅₀ = 0.39 ± 0.01 μmol/L) 进行了评估。不同含量多酚杂质的岩藻依聚糖部分或完全降低黄瓜苷A的胚胎毒性作用的能力₇来自C. japonica已显示。