Declining mortality of cerebral venous sinus thrombosis with thrombocytopenia after SARS-CoV-2 vaccination,European Journal of Neurology

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Declining mortality of cerebral venous sinus thrombosis with thrombocytopenia after SARS-CoV-2 vaccination
European Journal of Neurology ( IF 5.1 ) Pub Date : 2021-09-18 , DOI: 10.1111/ene.15113
Anita van de Munckhof ₁ , Katarzyna Krzywicka ₁ , Diana Aguiar de Sousa ₂ , Mayte Sánchez van Kammen ₁ , Mirjam R Heldner ₃ , Katarina Jood _{4,

5} , Erik Lindgren _{4,

5} , Turgut Tatlisumak _{4,

5} , Jukka Putaala ₆ , Johanna A Kremer Hovinga ₇ , Saskia Middeldorp ₈ , Marcel Levi _{9,

10} , Marcel Arnold ₃ , José M Ferro ₂ , Jonathan M Coutinho ₁

Affiliation

Department of Neurology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Department of Neurosciences and Mental Health, Neurology Service, Hospital de Santa Maria/CHULN, University of Lisbon, Lisbon, Portugal.
Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Department of Neurology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
Department of Neurology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Department of Hematology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Department of Internal Medicine, Radboud Institute of Health Sciences (RIHS), Radboud University Medical Center, Nijmegen, The Netherlands.
Biomedical Research Centre, National Institute for Health Research, University College London Hospitals (UCLH), London, UK.
Department of Vascular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

High mortality rates have been reported in patients with cerebral venous sinus thrombosis (CVST) due to vaccine-induced immune thrombotic thrombocytopenia (VITT) after vaccination with adenoviral vector SARS-CoV-2 vaccines. The aim of this study was to evaluate whether the mortality of patients with CVST-VITT has decreased over time.

中文翻译：

SARS-CoV-2疫苗接种后伴有血小板减少的脑静脉窦血栓形成死亡率下降

据报道，在接种腺病毒载体 SARS-CoV-2 疫苗后，由于疫苗引起的免疫性血栓性血小板减少症 (VITT)，脑静脉窦血栓形成 (CVST) 患者的死亡率很高。本研究的目的是评估 CVST-VITT 患者的死亡率是否随着时间的推移而降低。

更新日期：2021-09-18

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