GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types.,Acta Neuropathologica

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GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types.
Acta Neuropathologica ( IF 12.7 ) Pub Date : 2021-09-18 , DOI: 10.1007/s00401-021-02369-1
Philipp Sievers _{1,

2} , Damian Stichel _{1,

2} , Martin Sill _{3,

4} , Daniel Schrimpf _{1,

2} , Dominik Sturm _{3,

5,

6} , Florian Selt _{3,

5,

7} , Jonas Ecker _{3,

5,

7} , Daniel Kazdal ₈ , Evelina Miele ₉ , Mariëtte E G Kranendonk ₁₀ , Bastiaan B J Tops ₁₀ , Patricia Kohlhof-Meinecke ₁₁ , Rudi Beschorner ₁₂ , Christof M Kramm ₁₃ , Martin Hasselblatt ₁₄ , Guido Reifenberger _{15,

16} , David Capper _{17,

18} , Pieter Wesseling _{10,

19} , Albrecht Stenzinger ₈ , Till Milde _{3,

5,

7} , Andrey Korshunov _{1,

2,

3} , Olaf Witt _{3,

5,

7} , Stefan M Pfister _{3,

4,

5} , Wolfgang Wick _{20,

21} , Andreas von Deimling _{1,

2} , David T W Jones _{3,

6} , Felix Sahm _{1,

2,

3}

Affiliation

Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, University Hospital Heidelberg, Heidelberg, Germany.
Pediatric Glioma Research Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ), German Consortium for Translational Cancer Research (DKTK), Heidelberg, Germany.
Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Department of Pediatric Onco-Hematology and Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Department of Pathology, Klinikum Stuttgart, Stuttgart, Germany.
Department of Neuropathology, University of Tübingen, Tübingen, Germany.
Division of Pediatric Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany.
Institute of Neuropathology, University Hospital Münster, Münster, Germany.
Institute of Neuropathology, Heinrich Heine University, Düsseldorf, Germany.
German Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Düsseldorf, Germany.
Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Neuropathology, Berlin, Germany.
German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Department of Pathology, Amsterdam University Medical Centers, Location VUmc and Brain Tumor Center Amsterdam, Amsterdam, The Netherlands.
Clinical Cooperation Unit Neurooncology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Department of Neurology and Neurooncology Program, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany.