This review is meant to describe the genetic associations with pediatric severe COVID-19 pneumonia and the postinfectious complication of the multisystem inflammatory syndrome in children (MIS-C). Multiple genetic approaches have been carried out, primarily in adults with extrapolation to children, including genome-wide association studies (GWAS), whole exome and whole genome sequencing (WES/WGS), and target gene analyses.

中文翻译：

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儿科 SARS-CoV-2 COVID-19 和儿童多系统炎症综合征的宿主遗传学。

本综述旨在描述儿童重症 COVID-19 肺炎和儿童多系统炎症综合征 (MIS-C) 感染后并发症的遗传关联。已经开展了多种遗传学方法，主要针对成人，并外推到儿童，包括全基因组关联研究 (GWAS)、全外显子组和全基因组测序 (WES/WGS) 以及目标基因分析。