Managing migraine is not always straight forward. Although many drugs are available, few have been shown in placebo controlled studies to have an effect long term. Archivist has reported from the adult literature before about calcitonin gene–related peptide (CGRP) and the treatment of migraine. All CGRP-targeted preventive treatments are monoclonal antibodies administered by injection that target the CGRP receptor or ligand. In adults, oral CGRP receptor antagonists are used for the treatment of migraine attacks but not for preventive treatment of migraine. On behalf of the ADVANCE Study Group, Ailani J et al [ N Engl …

中文翻译：

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每天一次口服治疗偏头痛

管理偏头痛并不总是直截了当的。尽管有许多药物可用，但很少有安慰剂对照研究显示出长期有效。档案管理员之前从成人文献中报道了降钙素基因相关肽 (CGRP) 和偏头痛的治疗。所有 CGRP 靶向预防性治疗都是通过注射给药的单克隆抗体，靶向 CGRP 受体或配体。在成人中，口服 CGRP 受体拮抗剂用于治疗偏头痛发作，但不用于偏头痛的预防性治疗。代表 ADVANCE 研究组，Ailani J 等人 [N Engl …