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Archives of Disease in Childhood ( IF 5.2 ) Pub Date : 2021-10-01 , DOI: 10.1136/archdischild-2021-323115
BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health

Lucina has always considered pectus excavatum (PE) to have cosmetic or psychological sequelae without cardiovascular or respiratory compromise. Chest pain and shortness of breath appear to be commonly reported with some studies suggesting a reduced FEV1 and FVC and other lung volumes. Do these underlying recognised abnormalities explain these symptoms and impact exercise capacity? Hardie W et al [ Pediatric Pulmonology 2021;56:2911–2917. DOI: 10.1002/ppul.25540] have assessed if the anatomic extent of pectus deformities [determined by the correction index (CI)] is associated with a pulmonary impairment at rest and during exercise. This team performed a retrospective review on 269 children with PE. This group completed a symptom questionnaire, cardiopulmonary exercise test (CPET), pulmonary function tests (PFT), and chest MRI. Of these patients, dyspnoea on exertion and chest pain was reported in 64% and 41%, respectively. Peak oxygen uptake (VO2) was reduced in 30% and classified as mild in two-thirds. A pulmonary limitation during exercise was identified in less than 3%. Ventilatory limitations on PFT was found in 26% and classified as mild in 85%. Obstruction was the most common abnormal pattern (11%). There were no differences between patients with normal or abnormal PFT patterns for the CI, VO2, or percentage reporting …

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文献中的亮点

Lucina 一直认为漏斗胸 (PE) 有美容或心理后遗症,而不会影响心血管或呼吸系统。胸痛和呼吸急促似乎是常见的报告,一些研究表明 FEV1 和 FVC 以及其他肺容量降低。这些潜在的公认异常是否可以解释这些症状并影响运动能力?Hardie W 等人 [儿科肺病学 2021;56:2911-2917。DOI: 10.1002/ppul.25540] 评估了胸骨畸形的解剖范围 [由矫正指数 (CI) 确定] 是否与休息和运动期间的肺损伤有关。该团队对 269 名 PE 儿童进行了回顾性审查。该组完成了症状问卷、心肺运动试验(CPET)、肺功能试验(PFT)和胸部MRI。在这些患者中,劳力性呼吸困难和胸痛的报告率分别为 64% 和 41%。峰值摄氧量 (VO2) 降低了 30%,三分之二被归类为轻度。不到 3% 的患者在运动过程中出现肺功能受限。26% 的患者发现 PFT 通气受限,85% 的患者归类为轻度。阻塞是最常见的异常模式 (11%)。对于 CI、VO2 或百分比报告,具有正常或异常 PFT 模式的患者之间没有差异……
更新日期:2021-09-17
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