There are few studies on non-obese fatty liver disease, the aims of this study was to analyze its prevalence, popular trends, and associated and predictive factors, so as to provide reference for its prevention and treatment.

Individuals with complete data of body mass index, sex, age, and abdominal ultrasound in Karamay Central Hospital from 2009 to 2016 were selected to analyze the prevalence and popular trends of non-obese fatty liver disease (body mass index <24 kg/m²), and associated and predictive factors.

Between 2009 and 2016, a total of 191,555 medical check-ups were included. The prevalence of non-obese fatty liver disease increased from 1.9% to 5.1% among general medical examinants (P<0.001), increased from 4.6% to 11.7% in non-obese individuals (P<0.001). Compared with the non-obese control group, the levels of age, body mass index, blood pressure, fasting blood glucose, triglycerides, total cholesterol and uric acid in the non-obese fatty liver group were higher (P<0. 05). Even among non-obese subjects, elevated body mass index was associated with a 0.63-fold increased risk for non-obese fatty liver disease (P<0.001, odds ratio=1.63, 95% confidence interval 1.54-1.72) for every one-unit increase in body mass index. The most common abnormal indicator of non-obese fatty liver disease was elevated triglycerides (44.2%), which was also the best predictor of non-obese fatty liver disease (area under the curve =0.795) in non-obese physical examinators.

The prevalence of non-obese fatty liver disease was high and increasing rapidly in Karamay. Triglycerides is the best predictor of non-obese fatty liver in non-obese physical examinators.

非肥胖性脂肪肝的研究较少，本研究旨在分析其患病率、流行趋势及相关及预测因素，为其防治提供参考。

选取克拉玛依市中心医院2009-2016年体重指数、性别、年龄、腹部超声数据完整的个体，分析非肥胖性脂肪肝（体重指数<24 kg/m ² )，以及相关的和预测的因素。

2009 年至 2016 年间，共纳入 191,555 次体检。在普通体检者中，非肥胖性脂肪肝的患病率从 1.9% 增加到 5.1%（磷<0.001)，在非肥胖个体中从 4.6% 增加到 11.7% (磷<0.001)。与非肥胖对照组相比，非肥胖脂肪肝组的年龄、体重指数、血压、空腹血糖、甘油三酯、总胆固醇和尿酸水平较高。磷<0。05)。即使在非肥胖受试者中，体重指数升高也与非肥胖脂肪肝风险增加 0.63 倍相关。磷<0.001, 优势比 = 1.63, 95% 置信区间 1.54-1.72) 体重指数每增加一个单位。非肥胖性脂肪肝最常见的异常指标是甘油三酯升高（44.2%），这也是非肥胖体检者非肥胖性脂肪肝的最佳预测指标（曲线下面积=0.795）。

在克拉玛依，非肥胖性脂肪肝的患病率很高并且迅速增加。在非肥胖体检者中，甘油三酯是非肥胖脂肪肝的最佳预测指标。