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One-Pot Synthesis of Pyrrolo[1,2-f]phenanthridines From 1-Arylpyrroles via Successive Palladium-Catalyzed Direct Arylations
European Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2021-09-17 , DOI: 10.1002/ejoc.202100766
Jian Zhang 1 , Xinzhe Shi 1 , Henri Doucet 1
Affiliation  

A wide variety of pyrrolo[1,2-f]phenanthridines can be obtained from commercially available compounds using only 2 mol% of easily available Pd(OAc)2 catalyst precursor and KOAc as inexpensive base. With this synthetic scheme, the introduction of desired functional groups at positions 5, 6, 7, 8, 10 and 11 of pyrrolo[1,2-f]phenanthridines is possible.
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中文翻译:

1-芳基吡咯通过连续钯催化直接芳基化一锅法合成吡咯并[1,2-f]菲啶

多种吡咯并[1,2- f ]菲啶可以从市售化合物中获得,仅使用 2 mol% 容易获得的 Pd(OAc) 2催化剂前体和 KOAc 作为廉价碱。通过该合成方案,可以在吡咯并[1,2- f ]菲啶的5、6、7、8、10和11位引入所需的官能团。
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更新日期:2021-09-17
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