Background

Endoscopy is increasingly being adopted for removing colloid cysts. However, the neuropsychological outcome and quality of life (QOL) have not been studied in detail. This study is to evaluate the efficacy of endoscopic excision on cognitive measures and QOL.

Methods

Patients with colloid cysts larger than 7 mm, undergoing endoscopy were prospectively studied concerning clinico-radiology, cognitive parameters (age and education adjusted), extent of resection and recurrence. A cross-sectional QOL assessment was additionally performed on endoscopic patients in comparison with cases who underwent microsurgery or standalone ventriculo-peritoneal (VP) shunt.

Results

A total of 22 endoscopic patients with a mean age of 34 years and a mean cyst diameter of 19 mm were studied. Gross total resection(GTR) could be achieved in all. Over a mean follow-up of 53.4 months, none had a recurrence, ventriculomegaly, or retreatment. Among neuropsychological parameters, digit span was the most affected before surgery. There was a broad-based improvement in the mean global cognitive score from 40.63(±10.4) at baseline to 50.25(±5.8) after endoscopy with maximum improvement in 'immediate recall.' The change in scores also had a significant inverse correlation with cyst size, with cysts larger than 18 mm, resulting in lower scores following endoscopy(R=−0.9, P=0.01). QOL was significantly influenced by visual and cognitive impairments and was better among endoscopic patients than similar microsurgery or VP shunt controls, with a significant difference in social and environmental domains(P=0.02).

Conclusion

Endoscopy is effective in achieving GTR and long-term control, with neuropsychological improvement correlated with cyst size. This is probably the first report to show QOL is influenced by cognitive parameters and is better following endoscopy than after microsurgery or VP shunt.

中文翻译：

---

胶体囊肿：内窥镜全切除术后的神经心理学结果、生活质量和长期控制

背景

内窥镜检查越来越多地被用于去除胶体囊肿。然而，尚未详细研究神经心理学结果和生活质量（QOL）。本研究旨在评估内窥镜切除术对认知测量和生活质量的影响。

方法

对接受内窥镜检查的胶体囊肿大于 7 毫米的患者进行了前瞻性研究，涉及临床放射学、认知参数（年龄和教育程度调整）、切除范围和复发。与接受显微手术或独立脑室-腹膜 (VP) 分流术的病例相比，还对内窥镜患者进行了横断面 QOL 评估。

结果

共研究了 22 名平均年龄为 34 岁、平均囊肿直径为 19 mm 的内镜患者。全部可实现全切除（GTR）。在平均 53.4 个月的随访中，没有人出现复发、脑室扩大或再治疗。在神经心理参数中，手指跨度在手术前受到的影响最大。在内窥镜检查后，平均全球认知评分有广泛的改善，从基线时的 40.63(±10.4) 到 50.25(±5.8)，“立即回忆”的改善最大。评分的变化也与囊肿大小呈显着负相关，囊肿大于 18 mm，导致内镜检查后评分较低（R=-0.9，P=0.01）。

结论

内窥镜检查可有效实现 GTR 和长期控制，神经心理改善与囊肿大小相关。这可能是第一个显示 QOL 受认知参数影响的报告，并且在内窥镜检查后比显微手术或 VP 分流后更好。