Background Pediatric mild traumatic brain injury (mTBI) affects millions of children annually. Diffusion tensor imaging (DTI) is sensitive to axonal injuries and white matter microstructure and has been used to characterize the brain changes associated with mild traumatic brain injury (mTBI). Neurite orientation dispersion and density imaging (NODDI) is a diffusion model that can provide additional insight beyond traditional DTI metrics, but has not been examined in pediatric mTBI. The goal of this study was to employ DTI and NODDI to gain added insight into white matter alterations in children with mTBI compared to children with mild orthopedic injury (OI).

中文翻译：

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小儿轻度创伤性脑损伤后的脑白质：弥散张量和神经突定向和弥散成像研究

背景小儿轻度创伤性脑损伤 (mTBI) 每年影响数百万儿童。弥散张量成像 (DTI) 对轴突损伤和白质微观结构敏感，已被用于表征与轻度创伤性脑损伤 (mTBI) 相关的大脑变化。神经突取向分散和密度成像 (NODDI) 是一种扩散模型，可以提供超出传统 DTI 指标的额外洞察力，但尚未在儿科 mTBI 中进行检查。本研究的目的是使用 DTI 和 NODDI 来进一步了解 mTBI 儿童与轻度骨科损伤 (OI) 儿童相比的白质改变。