The aortic regurgitation (AR) index, proposed as an objective indicator of postprocedural AR, decreases in proportion to AR severity, besides reportedly providing additional prognostic information. Meanwhile, left ventricular (LV) function has also been considered an essential prognostic factor. This study aimed to clarify whether LV function affected the AR index using cardiac catheterization data.

A retrospective study was performed in patients whose LV function was evaluated using a micromanometer-tipped catheter. Patients with grade 2 or higher AR were excluded to explore non-AR factors affecting the AR index value. The AR index was calculated as a ratio of the gradient between the aortic diastolic blood pressure (DBP) and the LV end-diastolic pressure (EDP) to the aortic systolic blood pressure (SBP): AR Index = [ (DBP − LVEDP) / SBP] × 100.

A total of 64 patients [age, 62 (interquartile range: 48-70) years; LV ejection fraction, 19% (16%-26%) ] were examined. AR index values ranged from 18.3 to 68.6. Despite having no AR, two patients displayed an AR index < 25, indicating significant AR. Multiple-regression analysis revealed that LV diastolic stiffness (β = −0.750, P < 0.001), LV max dP/dt (β = −0.296, P = 0.006), and heart rate (β = 0.284, P = 0.011) were independent determinants of the AR index value.

Patients with impaired LV diastolic function and preserved systolic function had low AR index values. The additional prognostic information of the AR index may be related to LV diastolic function.

主动脉瓣关闭不全 (AR) 指数被提议作为术后 AR 的客观指标，除了据报道提供额外的预后信息外，还与 AR 的严​​重程度成比例地下降。同时，左心室（LV）功能也被认为是一个重要的预后因素。本研究旨在使用心导管术数据阐明 LV 功能是否影响 AR 指数。

对使用微压计尖端导管评估左室功能的患者进行了一项回顾性研究。排除 2 级或更高 AR 的患者以探索影响 AR 指数值的非 AR 因素。AR 指数计算为主动脉舒张压 (DBP) 和 LV 舒张末期压 (EDP) 与主动脉收缩压 (SBP) 之间的梯度比：AR 指数 = [ (DBP - LVEDP) /收缩压] × 100。

共64名患者[年龄，62（四分位距：48-70）岁；LV 射血分数，19% (16%-26%)] 被检查。AR 指数值介于 18.3 至 68.6 之间。尽管没有 AR，但两名患者的 AR 指数 < 25，表明 AR 显着。多元回归分析显示 LV 舒张期硬度 ( β = -0.750, P < 0.001)、LV max dP/dt ( β = -0.296, P = 0.006) 和心率 ( β = 0.284, P = 0.011) 是独立的AR 指数值的决定因素。

LV 舒张功能受损和收缩功能保留的患者的 AR 指数值较低。AR 指数的附加预后信息可能与 LV 舒张功能有关。