In this issue of Chem Catalysis, Walczak and co-workers introduce a carbastannatrane alanine derivative that facilitates amino acid side-chain functionalizations via C–C, C–S, and C–Se bond formation using Stille cross-coupling reactions. Applications in late-stage peptide modifications and macrocyclizations further exemplify the value of this novel building block.

中文翻译：

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用于肽修饰的有机金属试剂

在本期Chem Catalysis 中，Walczak 和同事介绍了一种 carbastannatrane 丙氨酸衍生物，该衍生物通过使用 Stille 交叉偶联反应形成 C-C、C-S 和 C-Se 键来促进氨基酸侧链功能化。在后期肽修饰和大环化中的应用进一步证明了这种新型构件的价值。