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Population-Based Study of Bloodstream Infection Incidence and Mortality Rates, Finland, 2004–2018
Emerging Infectious Diseases ( IF 11.8 ) Pub Date : 2021-09-15 , DOI: 10.3201/eid2710.204826
Keiju S K Kontula , Kirsi Skogberg , Jukka Ollgren , Asko Järvinen , Outi Lyytikäinen

We evaluated the incidence, outcomes, and causative agents of bloodstream infections (BSI) in Finland during 2004–2018 by using data from the national registries. We identified a total of 173,715 BSIs; annual incidence increased from 150 to 309 cases/100,000 population. BSI incidence rose most sharply among persons >80 years of age. The 1-month case-fatality rate decreased from 13.0% to 12.6%, but the 1-month all-cause mortality rate rose from 20 to 39 deaths/100,000 population. BSIs caused by Escherichia coli increased from 26% to 30% of all BSIs. BSIs caused by multidrug-resistant microbes rose from 0.4% to 2.8%, mostly caused by extended-spectrum β-lactamase-producing E. coli. We observed an increase in community-acquired BSIs, from 67% to 78%. The proportion of patients with severe underlying conditions rose from 14% to 23%. Additional public health and healthcare prevention efforts are needed to curb the increasing trend in community-acquired BSIs and antimicrobial drug–resistant E. coli.



中文翻译:

基于人群的血流感染发生率和死亡率研究,芬兰,2004–2018 年

我们使用国家登记处的数据评估了 2004-2018 年芬兰血流感染 (BSI) 的发生率、结果和病原体。我们总共确定了 173,715 个 BSI;年发病率从 150 例/100,000 人增加到 309 例。BSI 发病率在> 80 岁的人群中上升最为迅速。1 个月的病死率从 13.0% 下降到 12.6%,但 1 个月的全因死亡率从每 100,000 人的 20 人上升到 39 人。由大肠杆菌引起的 BSI从所有 BSI 的 26% 增加到 30%。由多重耐药微生物引起的 BSI 从 0.4% 上升到 2.8%,主要是由产超广谱 β-内酰胺酶的大肠杆菌引起的。我们观察到社区获得的 BSI 从 67% 增加到 78%。患有严重基础疾病的患者比例从14%上升到23%。需要额外的公共卫生和医疗保健预防工作来遏制社区获得性 BSI 和抗微生物药物大肠杆菌的增长趋势。

更新日期:2021-09-16
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