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Ignition sequence start: epithelial allergen sensing and regulation of the allergic inflammatory response
Nature Immunology ( IF 30.5 ) Pub Date : 2021-09-16 , DOI: 10.1038/s41590-021-01005-0
Ryan C Murphy 1, 2 , Matthew C Altman 3, 4
Affiliation  

Environmental allergens trigger activation of the ripoptosome in epithelial cells, which mediates the initial allergic response via intracellular processing and release of the alarmin IL-33 and represents a newly identified mechanism for epithelial allergen sensing.

中文翻译:

点火序列开始:上皮过敏原感应和过敏炎症反应的调节

环境过敏原触发上皮细胞中核糖体的激活,其通过细胞内加工和释放警报素 IL-33 介导最初的过敏反应,并代表了一种新发现的上皮过敏原传感机制。
更新日期:2021-09-16
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