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SPYing on triplet repeat expansions: Insights into FAN1-MLH1 interaction and regulation
Cell Reports ( IF 8.8 ) Pub Date : 2021-09-14 , DOI: 10.1016/j.celrep.2021.109736
Robert S Lahue 1
Affiliation  

The DNA repair proteins FAN1 and MLH1 have opposing effects on triplet repeat expansions. New studies by Goold et al. (2021) and Porro et al. (2021) pinpoint interactions between FAN1 and MLH1 that cross-regulate each other’s activities.



中文翻译:

监视三重重复扩展:深入了解 FAN1-MLH1 相互作用和调控

DNA 修复蛋白 FAN1 和 MLH1 对三重重复扩增具有相反的作用。古尔德等人的新研究。(2021) 和 Porro 等人。(2021) 查明 FAN1 和 MLH1 之间相互调节彼此活动的相互作用。

更新日期:2021-09-15
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