当前位置: X-MOL 学术J. Biomater. Sci. Polym. Ed. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
A review on the synthesis and properties of hydroxyapatite for biomedical applications
Journal of Biomaterials Science, Polymer Edition ( IF 3.6 ) Pub Date : 2021-10-03 , DOI: 10.1080/09205063.2021.1980985
V G DileepKumar 1 , Mysore Santosh Sridhar 2 , Pornanong Aramwit 3, 4 , Valentina K Krut'ko 5 , Olga N Musskaya 5 , Ilya E Glazov 5 , Narendra Reddy 1
Affiliation  

Abstract

Hydroxyapatite (HA or HAp) is one of the most preferred biomaterials, specifically for bone tissue engineering. HAp is available naturally and is also chemically synthesized. The properties, shape, size and crystalline structure and applications of HAp vary widely depending on the source and extraction methods used. In addition to conventional chemical approaches such as precipitation or sol-gel techniques, newer methods such as microwave synthesis and atomic-layer deposition provide an opportunity to generate HAp with desirable structure and properties. Various methods used for the synthesis of HAp have their own pros and cons. Hence, it is essential to understand the role of specific methods and conditions on the properties and structure of HAps in order to obtain HAp with properties suitable for specific applications. In addition to pure HAp, substantial efforts have been made to dope HAp with various minerals or bioentities to enhance their suitability for medical, environmental remediation and other approaches. In this review, we provide an overview of the various chemical methods used to produce HAp, properties of the HAp produced and its potential applications. Particular focus of this paper is on the co-relation between properties and processes used to synthesis HAp. This review will enable readers to quickly understand the importance of synthesis methods and conditions on the properties of HAp and choose appropriate means to generate HAp with desired properties for specific applications.



中文翻译:

用于生物医学应用的羟基磷灰石的合成和性质综述

摘要

羟基磷灰石(HA 或 HAp)是最优选的生物材料之一,特别是用于骨组织工程。HAp 是天然可用的,也是化学合成的。HAp 的性质、形状、尺寸和晶体结构以及应用因来源和使用的提取方法而异。除了沉淀或溶胶-凝胶技术等传统化学方法外,微波合成和原子层沉积等较新方法提供了生成具有理想结构和性能的 HAp 的机会。用于合成 HAp 的各种方法各有利弊。因此,必须了解特定方法和条件对 HAp 的性质和结构的作用,以获得具有适合特定应用的性质的 HAp。除了纯HAp,已经做出了大量努力来用各种矿物质或生物实体掺杂 HAp,以增强它们对医疗、环境修复和其他方法的适用性。在这篇综述中,我们概述了用于生产 HAp 的各种化学方法、所生产的 HAp 的特性及其潜在应用。本文特别关注用于合成 HAp 的特性和工艺之间的相互关系。本综述将使读者能够快速了解​​合成方法和条件对 HAp 特性的重要性,并选择适当的方法来生成具有特定应用所需特性的 HAp。我们概述了用于生产 HAp 的各种化学方法、所生产的 HAp 的特性及其潜在应用。本文特别关注用于合成 HAp 的特性和工艺之间的相互关系。本综述将使读者能够快速了解​​合成方法和条件对 HAp 特性的重要性,并选择适当的方法来生成具有特定应用所需特性的 HAp。我们概述了用于生产 HAp 的各种化学方法、所生产的 HAp 的特性及其潜在应用。本文特别关注用于合成 HAp 的特性和工艺之间的相互关系。本综述将使读者能够快速了解​​合成方法和条件对 HAp 特性的重要性,并选择适当的方法来生成具有特定应用所需特性的 HAp。

更新日期:2021-10-03
down
wechat
bug