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Increased incidence of severe nutritional anaemia in Yorkshire and Humber during the COVID-19 pandemic with critical clinical decompensation
Archives of Disease in Childhood ( IF 5.2 ) Pub Date : 2021-12-01 , DOI: 10.1136/archdischild-2021-322217
Kate Parmenter 1 , Andrew Brookes 2 , Sarah Burn 3 , Emma Gamwell 2 , Peter Jenkins 4 , Maria McPhee 5 , Sarah Webb 6 , Rajeeva Singh 7 , Sal Uka 5 , Beki James 8
Affiliation  

Over the last year, the Yorkshire and Humber region has seen an increased incidence of severe nutritional anaemia (NA) presenting with cardiovascular compromise and systemic decompensation. We hypothesise that this is, in part at least, arising as an indirect consequence of the current COVID-19 pandemic. We retrospectively analysed data from the seven paediatric departments in our region, identifying all children <16 years of age presenting with severe anaemia (haemoglobin (Hb) <50 g/L) between 1 January 2019 and 31 December 2020. One hundred and eighty-seven cases were identified, including 60 cases of NA (table 1), the vast majority of which were due to iron deficiency. Although the number of severe NA cases diagnosed fell from 34 in 2019 to 26 during the pandemic in 2020, the actual severity of anaemia at presentation was increased (figure 1). There was a significant drop in mean Hb at presentation from 40g/L in 2019 to 33g/L in 2020 (p=0.024), reflecting a doubling of cases with critical anaemia (Hb <30 g/L) in 2020 …

中文翻译:

在 COVID-19 大流行期间,约克郡和亨伯郡严重营养性贫血的发生率增加,并伴有严重的临床失代偿

在过去的一年中,约克郡和亨伯地区的严重营养性贫血 (NA) 发生率增加,表现为心血管损害和全身失代偿。我们假设这至少部分是当前 COVID-19 大流行的间接后果。我们回顾性分析了我们地区七个儿科部门的数据,确定了 2019 年 1 月 1 日至 2020 年 12 月 31 日期间出现严重贫血(血红蛋白 (Hb) <50 g/L)的所有 16 岁以下儿童。一百八十确定了 7 例,包括 60 例 NA(表 1),其中绝大多数是由于缺铁引起的。尽管确诊的严重 NA 病例数从 2019 年的 34 例下降到 2020 年大流行期间的 26 例,就诊时贫血的实际严重程度有所增加(图 1)。就诊时的平均 Hb 从 2019 年的 40g/L 显着下降到 2020 年的 33g/L(p=0.024),反映出 2020 年重症贫血(Hb <30 g/L)病例翻了一番……
更新日期:2021-11-19
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