Bactrocera dorsalis and its larvae have evolved to cope with the hypoxic environment during their lifetime. In this study, we sequenced the transcriptomes of B. dorsalis under and post anoxia stress. Our data revealed the different biological mechanisms of B. dorsalis in response to anoxia and during recovery from anoxia. The induction of heat shock proteins (HSPs) might be one of the important mechanisms for B. dorsalis to tolerate anoxia. Furthermore, our data showed B. dorsalis acquires energy through gluconeogenesis rather than glycolysis under anoxia and upregulated its lipid metabolism post anoxia. The up-regulation of the genes involved in the Hippo signaling pathway might also play a role in eliminating damaged cells as a result of anoxia. Furthermore, the HIF system of B. dorsalis did not change in response to anoxia stress in this study. We hypothesized that the HIF system in B. dorsalis might be activated by a specific duration of anoxia.

Bactrocera dorsalis及其幼虫在其一生中已经进化到可以应对缺氧环境。在这项研究中，我们对缺氧胁迫下和后背侧拟南芥的转录组进行了测序。我们的数据揭示了B. dorsalis响应缺氧和从缺氧恢复期间的不同生物学机制。热休克蛋白 (HSP) 的诱导可能是B. dorsalis耐受缺氧的重要机制之一。此外，我们的数据显示B. dorsalis在缺氧下通过糖异生而不是糖酵解获得能量，并在缺氧后上调其脂质代谢。参与 Hippo 信号通路的基因的上调也可能在消除因缺氧而受损的细胞方面发挥作用。此外，在本研究中，B. dorsalis的 HIF 系统没有响应缺氧压力而发生变化。我们假设B. dorsalis中的 HIF 系统可能被特定的缺氧持续时间激活。