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New analytical methods using carbon-based nanomaterials for detection of Salmonella species as a major food poisoning organism in water and soil resources
Chemosphere ( IF 8.8 ) Pub Date : 2021-09-14 , DOI: 10.1016/j.chemosphere.2021.132243
Behnaz Bakhshandeh 1 , Shokufeh Ghasemian Sorboni 2 , Dorrin Mohtadi Haghighi 3 , Fatemeh Ahmadi 4 , Zahra Dehghani 5 , Alireza Badiei 6
Affiliation  

Salmonella is one of the most prevalent causing agents of food- and water-borne illnesses, posing an ongoing public health threat. These food-poisoning bacteria contaminate the resources at different stages such as production, aggregation, processing, distribution, as well as marketing. According to the high incidence of salmonellosis, effective strategies for early-stage detection are required at the highest priority. Since traditional culture-dependent methods and polymerase chain reaction are labor-intensive and time-taking, identification of early and accurate detection of Salmonella in food and water samples can prevent significant health economic burden and lessen the costs. The immense potentiality of biosensors in diagnosis, such as simplicity in operation, the ability of multiplex analysis, high sensitivity, and specificity, have driven research in the evolution of nanotechnology, innovating newer biosensors. Carbon nanomaterials enhance the detection sensitivity of biosensors while obtaining low levels of detection limits due to their possibility to immobilize huge amounts of bioreceptor units at insignificant volume. Moreover, conjugation and functionalization of carbon nanomaterials with metallic nanoparticles or organic molecules enables surface functional groups. According to these remarkable properties, carbon nanomaterials are widely exploited in the development of novel biosensors. To be specific, carbon nanomaterials such as carbon nanotubes, graphene and fullerenes function as transducers in the analyte recognition process or surface immobilizers for biomolecules. Herein the potential application of carbon nanomaterials in the development of novel Salmonella biosensors platforms is reviewed comprehensively. In addition, the current problems and critical analyses of the future perspectives of Salmonella biosensors are discussed.



中文翻译:

使用碳基纳米材料检测作为水和土壤资源中主要食物中毒生物的沙门氏菌的新分析方法

沙门氏菌是最常见的食物和水传播疾病病原体之一,对公共健康构成持续威胁。这些食物中毒细菌在生产、聚集、加工、分销和销售等不同阶段污染资源。根据沙门氏菌病的高发病率,最优先需要早期检测的有效策略。由于传统的培养依赖方法和聚合酶链反应是劳动密集型和耗时的,因此早期准确检测沙门氏菌食品和水样中的检测可以防止重大的健康经济负担并降低成本。生物传感器在诊断方面的巨大潜力,例如操作简单、多重分析能力、高灵敏度和特异性,推动了纳米技术发展的研究,创新了更新的生物传感器。碳纳米材料提高了生物传感器的检测灵敏度,同时由于它们可以以微不足道的体积固定大量生物受体单元而获得低水平的检测限。此外,碳纳米材料与金属纳米粒子或有机分子的共轭和功能化使表面官能团成为可能。根据这些显着的特性,碳纳米材料被广泛用于开发新型生物传感器。再具体一点,碳纳米材料,如碳纳米管、石墨烯和富勒烯,在分析物识别过程中充当传感器或生物分子的表面固定剂。碳纳米材料在新材料开发中的潜在应用沙门氏菌生物传感器平台进行了全面审查。此外,还讨论了沙门氏菌生物传感器的当前问题和对未来前景的批判性分析。

更新日期:2021-09-17
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