Improper addition of melamine in milk powder poses a threat to human health, but the interference of complex components makes the trace detection hard. The cerium dioxide@carbon quasi-aerogels (CeO₂@C-QAs) with Schottky barrier was successfully prepared to detect melamine in milk powder. The interfacial effects of Schottky barrier on electrochemical detection are studied and find energy barrier can be used as a novel electrochemical driving factor to achieve anti-interference sensing. The highly sensitive detection of melamine was achieved at acidic and alkaline environments. It obtained the good recovery rate and exhibited anti-interference in real milk powder detection. The lowest detection limit (2.19 nM) was much lower than the international safety threshold of melamine content. It affords an inspiring chance to achieve anti-interference electrochemical detection by using the interfacial energy barrier effects.

奶粉中三聚氰胺添加不当对人体健康构成威胁，但复杂成分的干扰使得痕量检测变得困难。二氧化铈@碳准气凝胶（CeO ₂@C-QAs) 与肖特基屏障成功制备检测奶粉中的三聚氰胺。研究了肖特基势垒对电化学检测的界面效应，发现能量势垒可以作为一种新型的电化学驱动因素来实现抗干扰传感。三聚氰胺的高灵敏度检测是在酸性和碱性环境中实现的。在实际奶粉检测中获得了良好的回收率和抗干扰性。最低检测限（2.19 nM）远低于三聚氰胺含量的国际安全阈值。它为利用界面能垒效应实现抗干扰电化学检测提供了一个鼓舞人心的机会。