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Cell states can give tumorigenesis a head start
Nature Reviews Cancer ( IF 78.5 ) Pub Date : 2021-09-14 , DOI: 10.1038/s41568-021-00410-9
Sarah Seton-Rogers 1
Affiliation  

Using zebrafish and human pluripotent stem cell-derived models of melanoma, Baggiolini, Callahan et al. demonstrate that cells expressing progenitor-like programmes and specific chromatin-modifying enzymes are more readily transformed by BRAFV600E.

中文翻译:

细胞状态可以为肿瘤发生提供先机

使用斑马鱼和人类多能干细胞衍生的黑色素瘤模型,Baggiolini,Callahan 等人。证明表达祖细胞样程序和特定染色质修饰酶的细胞更容易被 BRAFV600E 转化。
更新日期:2021-09-14
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