Herein are reported initial efforts to develop a generally accessible flow process, applying a heterogenous nanocatalyst to aqueous micelle-enabled Suzuki–Miyaura coupling reactions. Also disclosed is a new engineering solution (i.e., a self-draining back pressure regulator), which, when applied, enabled 1.5 hours of continuous operation leading to the production of 20 grams of a pharmaceutical intermediate.

中文翻译：

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利用新型固体处理设备在水中连续浆液塞流 Fe/ppm Pd 纳米粒子催化 Suzuki-Miyaura 偶联

本文报道了开发普遍可及的流动过程的初步努力，将异质纳米催化剂应用于水性胶束启用的 Suzuki-Miyaura 偶联反应。还公开了一种新的工程解决方案（即自排放背压调节器），当应用该解决方案时，能够连续运行1.5小时，从而生产20克药物中间体。