Cyclotides are natural occurring microproteins found in plants that are stabilized by three disulfide bonds and a head-to-tail circular backbone forming a cyclic cystine-knot (CCK) motif. Here, the suite of cyclotides obtained from butterfly pea plant (Clitoria ternatea) is described using a diagnostic method that rapidly classifies the sequences as Möbius or Bracelet subtypes on the basis of mass-spectral product ion fingerprints caused by the Xxx-Pro bond fragmentation in complex, natural, microheterogeneous peptide libraries. More information can be found in the Full Paper by Neha V. Kalmankar, Padmanabhan Balaram, and Radhika Venkatesan.

中文翻译：

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封面：来自 Clitoria ternatea 的环肽的质谱分析：Xxx-Pro 键断裂作为 Pro 残基定位的便捷诊断（Chem. Asian J. 19/2021）

环肽是在植物中发现的天然微生物蛋白，通过三个二硫键和形成环状胱氨酸结 (CCK) 基序的头对尾环状骨架稳定。在这里，使用一种诊断方法描述了从蝴蝶豌豆植物（Clitoria ternatea）中获得的环肽套件，该方法根据由 Xxx-Pro 键断裂引起的质谱产物离子指纹快速将序列分类为 Möbius 或 Bracelet 亚型。复杂、天然、微异质的肽库。更多信息可以在 Neha V. Kalmankar、Padmanabhan Balaram 和 Radhika Venkatesan 的全文中找到。