Abstract

Two new chromones named cnidimol G (1) and cnidimol H (2), one new coumarin, 7-methoxy-8-(3-methoxy-3-methyl-2-oxobutyl)coumarin (3), and twenty known compounds were isolated from MeOH extract of the fruit of Cnidium monnieri (L.) Cusson. The structures of compounds were elucidated by extensive spectroscopic analyses including 1 D and 2 D NMR, HRESIMS, IR and UV. Anti-inflammatory activity of the selected isolated compounds were evaluated. Compounds 1 and 8 exhibited inhibitory activities against nitric oxide production.

中文翻译：

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Cnidium monnieri (L.) Cusson 果实中的两种新色酮和一种新香豆素

摘要

分离出两种新的色酮化合物 cnidimol G ( 1 ) 和 cnidimol H ( 2 )、一种新的香豆素 7-methoxy-8-(3-methoxy-3-methyl-2-oxobutyl)coumarin ( 3 ) 以及二十种已知化合物来自Cnidium monnieri (L.) Cusson果实的 MeOH 提取物。化合物的结构通过广泛的光谱分析阐明，包括 1 D 和 2 D NMR、HRESIMS、IR 和 UV。评估了所选分离化合物的抗炎活性。化合物1和8对一氧化氮的产生具有抑制活性。