Prostate cancer (PCa) is more frequent and more aggressive in populations of African descent than in Caucasians. Since the fatty acid composition of peri-prostatic adipose tissue (PPAT) has been shown to differ according to the ethno-geographic origin and is involved in PCa aggressiveness, we aimed to analyze the cholesterol content of PPAT from Caucasian and African-Caribbean patients, in correlation with markers of disease aggressiveness and cholesterol metabolism in cancer tissues.

中文翻译：

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组织胆固醇代谢和前列腺癌侵袭性：民族地理变异

与高加索人相比，非洲裔人群的前列腺癌 (PCa) 更常见且更具侵袭性。由于已显示前列腺周围脂肪组织 (PPAT) 的脂肪酸组成因民族地理起源而异，并且与 PCa 侵袭性有关，因此我们旨在分析高加索和非洲加勒比患者的 PPAT 的胆固醇含量，与癌症组织中疾病侵袭性和胆固醇代谢的标志物相关。