Introduction: There is limited study comparing dosimetry parameters in detail. In regard to prostate cancer, there are four different techniques, namely three-dimensional conformal radiotherapy (3D-CRT), intensity-modulated radiotherapy-step and shoot (IMRT-SS), IMRT-helical tomotherapy (HT), and volumetric-modulated arc therapy (VMAT).
Materials and Methods: Experimental study with intervention on ten prostate cancer patients' computed tomography planning data. 78 Gy dose in 39 fractions was given for planning target volume.Experimental study with intervention on ten prostate cancer patients' computed tomography planning data. 78 Gy dose in 39 fractions was given for planning target volume.
Results: The mean V75 Gy rectum and bladder between 3D-CRT and the other three abovementioned techniques all showed significant results (P < 0.05). V5 Gy remaining volume at risk (RVR) between 3D-CRT versus VMAT and HT, IMRT-SS versus HT, and VMAT versus HT is statistically significant (P < 0.0001). The longest radiation time was done with HT (mean 4.70 ± 0.84 min).
Conclusion: V75 Gy rectum bladder between 3D-CRT techniques differ significantly compared to the three other techniques and may not be suitable to the implementation of escalation doses. The HT technique produced the highest V5 Gy RVR and needed the highest monitor unit amount and the longest radiation duration. The VMAT technique was considered capable of realizing dose escalation in prostate cancer radiotherapy by minimizing toxicity in the rectum and bladder with the shortest radiation duration.


中文翻译：

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前列腺癌放疗中三维适形放疗、调强放疗、步进和射击、螺旋断层放疗和体积调制弧治疗的剂量学分析


简介：详细比较剂量学参数的研究有限。关于前列腺癌，有四种不同的技术，即三维适形放射治疗（3D-CRT）、调强放疗-步进和射击（IMRT-SS）、IMRT-螺旋断层放疗（HT）和体积调制电弧疗法（VMAT）。
材料和方法：对十名前列腺癌患者的计算机断层扫描计划数据进行干预的实验研究。计划靶区给予78 Gy 39 次剂量。对10 名前列腺癌患者CT 计划数据进行干预的实验研究。为规划目标体积，给予 39 次 78 Gy 剂量。
结果：3D-CRT 与上述其他三种技术之间的平均 V75 Gy 直肠和膀胱均显示出显着的结果（P <0.05）。3D-CRT 与 VMAT 和 HT、IMRT-SS 与 HT 以及 VMAT 与 HT 之间的 V5 Gy 剩余风险体积 (RVR) 具有统计学意义 ( P < 0.0001)。用 HT 完成的辐射时间最长（平均 4.70 ± 0.84 分钟）。
结论：与其他三种技术相比，3D-CRT 技术之间的 V75 Gy 直肠膀胱差异显着，可能不适合实施递增剂量。HT技术产生最高的V5 Gy RVR，需要最高的监测单位量和最长的辐射持续时间。VMAT技术被认为能够通过最小化直肠和膀胱中的毒性以最短的辐射持续时间实现前列腺癌放疗中的剂量递增。