To maintain cardiac output, the failing heart undergoes significant remodeling. However, the mechanisms regulating this remain unclear. In this issue of Immunity, Zaman et al. and Wong, Mohan, and Kopecky et al. uncover an interaction between resident cardiac macrophages and cardiomyocytes governing this process.

中文翻译：

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在心脏问题上，（蜂窝）通信是关键

为了维持心输出量，衰竭的心脏会经历显着的重塑。然而，调节这一点的机制仍不清楚。在本期《免疫》中，Zaman 等人。和 Wong、Mohan 和 Kopecky 等人。揭示常驻心脏巨噬细胞和控制这一过程的心肌细胞之间的相互作用。