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MARCH8 Restricts Influenza A Virus Infectivity but Does Not Downregulate Viral Glycoprotein Expression at the Surface of Infected Cells
mBio ( IF 6.4 ) Pub Date : 2021-09-14 , DOI: 10.1128/mbio.01484-21
Fernando Villalón-Letelier 1 , Andrew G Brooks 1 , Sarah L Londrigan 1 , Patrick C Reading 1, 2
Affiliation  

The antiviral activity of MARCH8 has been associated with the downregulation of envelope glycoproteins from a range of different viruses, resulting in reduced incorporation into nascent virions. Here, we show that MARCH8 restricts IAV at a late stage in ...

中文翻译:

MARCH8 限制甲型流感病毒的传染性,但不会下调受感染细胞表面的病毒糖蛋白表达

MARCH8 的抗病毒活性与一系列不同病毒的包膜糖蛋白的下调有关,从而导致新生病毒粒子的掺入减少。在这里,我们展示了 MARCH8 在 ...
更新日期:2021-09-14
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