Abstract

Background

Adherence and persistence to treatment are crucial in statin therapy as they are synonymous with efficacy and quality of care. The aim of this study was the real-life assessment of adherence and persistence over eight years in treatment-naive patients receiving atorvastatin, lovastatin, simvastatin, pravastatin, ezetimibe.

Methods

Adherence to treatment was calculated using the ‘proportion of days covered’ method and persistence as the difference between the start and end of the therapy under study.

Results

Treatment adherence was consistently above 85% for all drugs under study in each year. Treatment persistence was shown to half halved already from the first year.

Conclusion

Adherent patients had a higher persistence than non-adherent patients.

中文翻译：

---

在现实生活研究中坚持和坚持使用他汀类药物和依折麦布超过 8 年

摘要

背景

坚持和坚持治疗在他汀类药物治疗中至关重要，因为它们是疗效和护理质量的代名词。本研究的目的是对接受阿托伐他汀、洛伐他汀、辛伐他汀、普伐他汀、依折麦布的初治患者八年的依从性和持久性进行真实评估。

方法

使用“覆盖天数比例”方法计算对治疗的依从性，并将持久性作为研究治疗开始和结束之间的差异。

结果

每年研究中的所有药物的治疗依从性始终高于 85%。从第一年开始，治疗持久性已减半。

结论

依从性患者比非依从性患者具有更高的持久性。