Abstract: Dengue fever is a prevalent viral disease that primarily affects tropical nations. Although most symptomatic infections have a relatively benign course, a small percentage of patients experience severe clinical symptoms, such as bleeding and endothelial dysfunction, which can lead to hypovolemic shock and cardiovascular collapse. Dengue fever is now known to involve the heart by inducing myocardial inflammation, arrhythmias, and, in rare cases, fulminant myocarditis, up to 13% in severe dengue. Conduction abnormalities can range from benign sinus bradycardia to fulminant tachyarrhythmias and atrioventricular blocks. Although most conduction disturbances are benign and transient, they can occasionally aggravate pre-existing conditions and even be fatal. Unlike other viral myocarditis like hepatitis C induced myocarditis, dengue causes mainly transient changes, and long-term complications like dilated cardiomyopathy are not noted. There is indeed a paucity of data on how to assess and treat individuals with conduction abnormalities. In this review, the authors have discussed the wide variety of conduction abnormalities seen in dengue, their pathophysiology, clinical consequences, and a method for evaluating and managing these individuals.

Keywords: Dengue fever, Electrocardiography, Arrhythmia, Myocarditis


中文翻译：

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登革热心电图变化：文献综述

摘要：登革热是一种流行的病毒性疾病，主要影响热带国家。尽管大多数有症状的感染病程相对良性，但仍有一小部分患者出现严重的临床症状，如出血和内皮功能障碍，可导致低血容量性休克和心血管衰竭。现在已知登革热通过引起心肌炎症、心律失常以及在极少数情况下引起暴发性心肌炎而累及心脏，在严重登革热中高达 13%。传导异常的范围可以从良性窦性心动过缓到暴发性快速性心律失常和房室传导阻滞。尽管大多数传导障碍是良性和暂时性的，但它们偶尔会加重原有疾病，甚至是致命的。与其他病毒性心肌炎如丙型肝炎引起的心肌炎不同，登革热主要引起一过性变化，没有注意到扩张型心肌病等长期并发症。关于如何评估和治疗传导异常个体的数据确实很少。在这篇综述中，作者讨论了登革热的各种传导异常、它们的病理生理学、临床后果以及评估和管理这些个体的方法。

关键词：登革热，心电图，心律失常，心肌炎