Purpose. To determine the effects of cataract surgery and preoperative factors on the vision-related quality of life (QOL) in patients with retinitis pigmentosa (RP). Materials and Methods. This was a prospective, interventional study of 54 patients diagnosed with RP. The 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25) was used to determine the QOL before and after the cataract surgery. The correlations between the scores of the questionnaire and the best-corrected visual acuity (BCVA), macular structure, and degree of improvement of the NEI VFQ-25 scores were also determined. Results. Statistically significant improvements were observed in the BCVA and all of the NEI VFQ-25 subscale scores except for color vision. The improvement of general vision was the largest. The postoperative BCVA of the better-seeing eye was more strongly and significantly correlated with the postoperative NEI VFQ-25 scores than that of the worse-seeing eye. All of the postoperative NEI VFQ-25 scores were significantly correlated with the length of the ellipsoid zone (EZ) of the photoreceptors. No significant correlation was found between the preoperative general vision, near vision, mental health scores, and EZ length. All of the preoperative NEI VFQ-25 scores except the social function and mental health scores were negatively and significantly correlated with the degree of improvement of the NEI VFQ-25 score. The EZ length was significantly correlated with the degree of improvement of the NEI VFQ-25 scores of the general vision, distance vision, mental health, dependency, and composite 9 scores. Conclusions. Cataract surgery can significantly improve the NEI VFQ-25 scores in RP patients. The EZ length can be used to predict the postoperative VFQ scores. We conclude that the NEI VFQ-25 is a useful method to evaluate the impact of cataract surgery on the BCVA in patients with RP.

中文翻译：

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白内障手术对色素性视网膜炎患者视力相关生活质量的影响及生活质量改善的预测因素

目的。确定白内障手术和术前因素对视网膜色素变性（RP）患者视力相关生活质量（QOL）的影响。材料和方法。这是一项对 54 名诊断为 RP 的患者进行的前瞻性干预性研究。25项国家眼科研究所视觉功能问卷（NEI VFQ-25）用于确定白内障手术前后的生活质量。还确定了问卷分数与最佳矫正视力 (BCVA)、黄斑结构和 NEI VFQ-25 分数改善程度之间的相关性。结果. 在 BCVA 和除色觉之外的所有 NEI VFQ-25 分量表得分中观察到统计学上的显着改善。一般视力的改善是最大的。与视力较差眼相比，视力较好眼的术后 BCVA 与术后 NEI VFQ-25 评分的相关性更强且显着。所有术后 NEI VFQ-25 评分均与光感受器椭圆体区 (EZ) 的长度显着相关。术前一般视力、近视力、心理健康评分和EZ长度之间未发现显着相关性。除社会功能和心理健康评分外，所有术前NEI VFQ-25评分均与NEI VFQ-25评分改善程度呈显着负相关。结论。白内障手术可显着提高 RP 患者的 NEI VFQ-25 评分。EZ 长度可用于预测术后 VFQ 评分。我们得出结论，NEI VFQ-25 是评估白内障手术对 RP 患者 BCVA 影响的有用方法。