Herein, we offer some perspective on the metamorphosis that has already begun to take place in substantial parts of the chemical industry, i.e., a switch from traditional resources such as crude oil to biomass. This change requires the workhorse of chemical reactants and petroleum refineries to be replaced with biorefineries. The present perspective offers a brief look at the manufacture and uses of furan platform chemicals (FPCs) directly available from biomass (furfural and 5-hydroxy-methylfurfural). Next, we discuss the difficulties encountered when a secondary FPC, 2,5-furandicarboxylic acid, moves from the lab to large-scale manufacture. The main purpose of the present article is to show the spectacular range of compounds that can be economically synthesized from biomass via FPCs. The fate of selected FPCs and their potential are shown herein as an example only, where many more simple or complex chemicals can be obtained. We believe that there are excellent applications of bio-based materials besides the broadly promoted manufacture of fuels and monomers. This perspective looks at the types of reactions applicable to FPCs and a variety of methods for the synthesis of chiral furans.

中文翻译：

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燃料和塑料以外的呋喃平台化学品

在此，我们对化学工业的重要部分已经开始发生的转变提供了一些观点，即从传统资源（如原油）到生物质的转变。这种变化需要用生物炼油厂代替化学反应物和炼油厂的主力。本观点简要介绍了可直接从生物质（糠醛和 5-羟基-甲基糠醛）中获得的呋喃平台化学品 (FPC) 的制造和使用。接下来，我们讨论了二级 FPC 2,5-呋喃二甲酸从实验室转移到大规模制造时遇到的困难。本制品的主要目的是要表明，可以从生物质经济地合成的化合物的壮观范围通过FPC。所选 FPC 的命运及其潜力仅作为示例在此显示，其中可以获得更多简单或复杂的化学品。我们相信，除了广泛推广的燃料和单体制造之外，生物基材料还有很好的应用。这个观点着眼于适用于 FPC 的反应类型和各种合成手性呋喃的方法。