Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients,Molecular Genetics & Genomic Medicine

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Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients
Molecular Genetics & Genomic Medicine ( IF 2 ) Pub Date : 2021-09-12 , DOI: 10.1002/mgg3.1764
Kelly S Levano ₁ , Luis Jaramillo-Valverde ₁ , David D Tarazona ₁ , Cesar Sanchez ₁ , Silvia Capristano ₁ , Tania Vásquez-Loarte ₁ , Lely Solari ₁ , Alberto Mendoza-Ticona ₂ , Alonso Soto _{3,

4} , Christian Rojas ₁ , Roberto Zegarra-Chapoñan ₁ , Heinner Guio _{1,

5,

6}

Affiliation

We determined the frequency of genetic polymorphisms in three anti-TB drug metabolic proteins previously reported: N-acetyltransferase 2 (NAT2), cytochrome P450 2E1 (CYP2E1), and arylacetamide deacetylase (AADAC) within a Peruvian population in a cohort of TB patients.

中文翻译：

秘鲁肺结核患者队列中 NAT2、CYP2E1 和 AADAC 基因的等位基因和基因型频率

我们确定了先前报道的三种抗结核药物代谢蛋白中基因多态性的频率：N-乙酰转移酶 2 ( NAT2 )、细胞色素 P450 2E1 ( CYP2E1 ) 和芳基乙酰胺脱乙酰酶 ( AADAC ) 在秘鲁人群中的结核病患者队列。

更新日期：2021-11-10

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