Carborane encapsulation was visualized by using fluoroboropyrrole (BODIPY) zwitterionic polymer as fluorescence marker. Firstly, a water-soluble fluorescent probe carrier was prepared by combining the BODIPY derivatives with poly (carboxybetaine methacrylate) (p-CBMA). Two oil-in-water carborane polymers were self-assembled in organic solvents by means of dual ion hydrogen bonding. The ultraviolet and fluorescence spectra were measured with different organic solvents, and the spectra ranged from 531 to 555 nm. The dynamic self-assembly effect was tested by TEM, and the internal microscopic phenomena of the water-soluble polymer were further observed. It was confirmed that two kinds of BODIPY zwitterionic polymers were firmly encase the fat-soluble carborane, forming an oval shape. Carboranes are water-soluble, can achieve biocompatible expression, and can visualize the degree of aggregation in the targeted cells through its own fluorescence effect. Subsequent imaging of the cells showed that both polymers entered the targeted cells.

通过使用氟硼吡咯 (BODIPY) 两性离子聚合物作为荧光标记物来观察碳硼烷封装。首先，通过将 BODIPY 衍生物与聚（羧基甜菜碱甲基丙烯酸酯）（p-CBMA）结合制备水溶性荧光探针载体。两种水包油碳硼烷聚合物通过双离子氢键在有机溶剂中自组装。紫外和荧光光谱用不同的有机溶剂测量，光谱范围为 531 至 555 nm。通过TEM测试动态自组装效应，进一步观察水溶性聚合物的内部微观现象。证实两种BODIPY两性离子聚合物牢固地包裹着脂溶性碳硼烷，形成椭圆形。碳硼烷是水溶性的，可以实现生物相容性表达，并且可以通过自身的荧光效应可视化目标细胞内的聚集程度。随后的细胞成像显示两种聚合物都进入了靶细胞。