This review summarizes the research that has recently been performed on in-capillary enzymatic reactions integrated with capillary electrophoresis. The manuscript is subdivided in homogeneous and heterogeneous approaches. The main homogeneous techniques are Electrophoretically Mediated Microanalysis, At-inlet and Transverse Diffusion of Laminar Flow Profiles. The main heterogeneous ones are Immobilized MicroEnzyme Reactors with enzymes grafted on either non-magnetic or magnetic particles. The overview covers the period from 2018 to early 2021. The applications range from drug discovery over natural products to food, beverage and pesticide analysis.

中文翻译：

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使用毛细管电泳的毛细管内酶促反应概述

这篇综述总结了最近在毛细管内酶促反应与毛细管电泳相结合的研究。手稿分为同质和异质方法。主要的均相技术是电泳介导的微量分析、入口处和层流剖面的横向扩散。主要的异质反应器是固定化微酶反应器，酶接枝在非磁性或磁性颗粒上。概述涵盖 2018 年至 2021 年初期间。应用范围从天然产物的药物发现到食品、饮料和农药分析。