Human urinary kallidinogenase in acute ischemic stroke: A single-arm, multicenter, phase IV study (RESK study),CNS Neuroscience & Therapeutics

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Human urinary kallidinogenase in acute ischemic stroke: A single-arm, multicenter, phase IV study (RESK study)
CNS Neuroscience & Therapeutics ( IF 5.5 ) Pub Date : 2021-09-12 , DOI: 10.1111/cns.13724
Jun Ni ₁ , Ming Yao ₁ , Li-Hua Wang ₂ , Ming Yu ₃ , Run-Hui Li ₄ , Li-Hong Zhao ₅ , Jia-Chun Wang ₆ , Yin-Zhou Wang ₇ , Xin Wang ₈ , Hai-Qing Song ₉ , Ben-Yan Luo ₁₀ , Jia-Wei Wang ₁₁ , Yi-Ning Huang ₁₂ , Li-Ying Cui ₁ ,

Affiliation

Department of Neurology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Department of Neurology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Department of Neurology, The Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Department of Neurology, Central Hospital Affiliated to Shenyang Medical College, Shenyang, China.
Department of Neurology, Dandong People's Hospital, Dandong, China.
Department of Neurology, No. 1 Hospital of Harbin, Harbin, China.
Department of Neurology, Fujian Provincial Hospital, Fuzhou, China.
Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai, China.
Department of Neurology, Xuanwu Hospital Capital Medical University, Beijing, China.
Department of Neurology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Department of Neurology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Department of Neurology, Peking University First Hospital, Beijing, China.

Human urinary kallidinogenase (HUK) has shown favorable efficacies in acute ischemic stroke (AIS) treatment. We sought confirmation of the safety and efficacy of HUK for AIS in a large population.

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