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CZT Detectors-Based SPECT Imaging: How Detector and Collimator Arrangement Can Determine the Overall Performance of the Tomograph
Electronics ( IF 2.9 ) Pub Date : 2021-09-11 , DOI: 10.3390/electronics10182230
Maria Filomena Santarelli , Anna Mori , Michelangelo Bertasi , Vincenzo Positano , Alessia Gimelli , Michele Scipioni , Paolo Marzullo , Luigi Landini

A technical comparison is described between two SPECT systems, one dedicated to cardiovascular studies and one general-purpose, to evaluate the advantages and disadvantages of their use in an organ-specific clinical setting. The comparison was made between a dedicated cardiac SPECT (Alcyone, Discovery NM 530c, GE Healthcare) scanner and a general-purpose one (Discovery NM/CT 670 CZT, GE Healthcare). The two scanners differ in terms of hardware, mainly in the arrangement of the detectors and collimators, which are the main components of SPECT. A standard NEMA phantom was used to characterize the energy resolution, spatial resolution, and sensitivity for the two systems. Then, using a custom-made cardiac phantom, more specific indices were computed to evaluate the quality of cardiac images, such as signal-to-background noise ratio (SBNR), tissue-background contrast-to-noise ratio (TBCNR), and uniformity. Finally, the same indices were computed for clinical images acquired with the two systems from 11 subjects. Alcyone showed superior performance for dedicated cardiac imaging; however, its excellent qualities are aimed only at the study of the heart and only at patients with a low body-mass index, unlike Discovery NM/CT 670 CZT, which can be used for every anatomic district area and for every type of patient.

中文翻译:

基于 CZT 探测器的 SPECT 成像:探测器和准直器的布置如何确定断层扫描仪的整体性能

描述了两个 SPECT 系统之间的技术比较,一个专门用于心血管研究,一个通用,以评估它们在特定器官临床环境中使用的优点和缺点。在专用心脏 SPECT(Alcyone,Discovery NM 530c,GE Healthcare)扫描仪和通用型(Discovery NM/CT 670 CZT,GE Healthcare)之间进行了比较。两种扫描仪在硬件方面有所不同,主要在于探测器和准直器的布置,它们是 SPECT 的主要组成部分。标准 NEMA 体模用于表征两个系统的能量分辨率、空间分辨率和灵敏度。然后,使用定制的心脏体模,计算更具体的指标来评估心脏图像的质量,例如信噪比 (SBNR)、组织背景对比度噪声比 (TBCNR) 和均匀性。最后,对使用这两个系统从 11 名受试者获得的临床图像计算了相同的指数。Alcyone 在专用心脏成像方面表现出卓越的性能;然而,与 Discovery NM/CT 670 CZT 不同,Discovery NM/CT 670 CZT 可用于每个解剖区域和每种类型的患者,它的卓越品质仅针对心脏研究和低体重指数患者。
更新日期:2021-09-12
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