Most commercially available sucrose esters are prepared using synthetic regimes that require volatile organic compounds as solvents. This results in high manufacturing costs, environmentally deleterious production processes, and products possessing residual toxicities. While solvent-free protocols can address these issues, they often lead to an inadequate monoester content in the final product and thereby lower the market value of the overall product mixture. Accordingly, we now report a practical synthetic protocol that delivers high-purity monostearate sucrose esters under solvent-free conditions. We also describe an effective ultraperformance convergence chromatography-mass spectrometric method for analyzing the synthesized monoesters. Under optimized conditions, the sucrose monoester component of our product mixture is 74.6 wt % and thus comparable to those of the best commercial preparations currently on the market. Evaluation of the emulsifying properties of the solvent-free-derived materials established that, in some cases, these were superior to their commercial counterparts. As such, the solvent-free protocol reported here represents both an economically attractive and environmentally friendly alternative to the potentially polluting sucrose ester production techniques currently employed by industry.

中文翻译：

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高纯蔗糖脂肪酸单酯的无溶剂合成及其与商业同类产品的性能比较

大多数市售蔗糖酯是使用需要挥发性有机化合物作为溶剂的合成方案制备的。这导致高制造成本、对环境有害的生产过程以及具有残留毒性的产品。虽然无溶剂方案可以解决这些问题，但它们通常会导致最终产品中单酯含量不足，从而降低整个产品混合物的市场价值。因此，我们现在报告一种实用的合成方案，可在无溶剂条件下提供高纯度的单硬脂酸蔗糖酯。我们还描述了一种有效的超高性能会聚色谱-质谱法，用于分析合成的单酯。在优化条件下，我们产品混合物的蔗糖单酯组分为 74。6 wt %，因此可与目前市场上最好的商业制剂相媲美。对无溶剂衍生材料的乳化性能的评估表明，在某些情况下，这些材料优于其商业同类产品。因此，这里报告的无溶剂协议代表了一种经济上有吸引力和环境友好的替代方案，可以替代目前工业采用的潜在污染蔗糖酯生产技术。