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Lipopolysaccharide preconditioning augments phagocytosis of malaria-parasitized red blood cells by bone marrow-derived macrophages in the liver, thereby increasing the murine survival after Plasmodium yoelii infection
Infection and Immunity ( IF 3.1 ) Pub Date : 2021-08-23 , DOI: 10.1128/iai.00249-21
Takeshi Ono 1 , Yoko Yamaguchi 1 , Hiroyuki Nakashima 2 , Masahiro Nakashima 2 , Takuya Ishikiriyama 2 , Shuhji Seki 2 , Manabu Kinoshita 2
Affiliation  

Malaria remains a grave concern for humans, as effective medical countermeasures for Plasmodium infection have yet to be developed. Phagocytic clearance of parasitized red blood cells (pRBCs) by macrophages is an important front-line innate host defense ...

中文翻译:

脂多糖预处理增强了肝脏中骨髓来源的巨噬细胞对疟原虫红细胞的吞噬作用,从而增加了约氏疟原虫感染后的小鼠存活率

疟疾仍然是人类严重关注的问题,因为尚未开发出有效的疟原虫感染医学对策。巨噬细胞对寄生红细胞 (pRBC) 的吞噬清除是重要的前线先天宿主防御...
更新日期:2021-09-12
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