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Transition-Metal-Free Cross-Dehydrogenative Couplings of 8-Aminoquinoline Amides at C5 Position with Acetonitrile, Ethers or Acetone
European Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2021-09-09 , DOI: 10.1002/ejoc.202100953 Da Liu 1 , Zhen Xia 1 , Yuanjiu Xiao 1 , Yongqi Yu 1 , Lin Yu 1 , Zenan Song 1 , Qianlong Wu 1 , Junhui Zhang 2 , Ze Tan 3
European Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2021-09-09 , DOI: 10.1002/ejoc.202100953 Da Liu 1 , Zhen Xia 1 , Yuanjiu Xiao 1 , Yongqi Yu 1 , Lin Yu 1 , Zenan Song 1 , Qianlong Wu 1 , Junhui Zhang 2 , Ze Tan 3
Affiliation
A novel and efficient method for highly regioselective cyanomethylation, etherification or acetonation of 8-aminoquinoline amides at C5 position was developed, and such reactions proceed under transition metal-free and base-free conditions.
中文翻译:
8-氨基喹啉酰胺在 C5 位与乙腈、醚或丙酮的无过渡金属交叉脱氢偶联
开发了一种新的高效方法,用于 C5 位 8-氨基喹啉酰胺的高度区域选择性氰甲基化、醚化或丙酮化,并且此类反应在无过渡金属和无碱条件下进行。
更新日期:2021-09-20
中文翻译:
8-氨基喹啉酰胺在 C5 位与乙腈、醚或丙酮的无过渡金属交叉脱氢偶联
开发了一种新的高效方法,用于 C5 位 8-氨基喹啉酰胺的高度区域选择性氰甲基化、醚化或丙酮化,并且此类反应在无过渡金属和无碱条件下进行。