Sub-Saharan Africa, which has a population of more than 1 billion people, carries 24% of the global burden of disease and spends the least on health care of any region, relying heavily on international development assistance to deliver health care for HIV, tuberculosis, and malaria. The demographic and epidemiological transitions occurring in sub-Saharan Africa, with rising prevalences of obesity and diabetes, enhance the risk of non-alcoholic fatty liver disease (NAFLD), yet this remains an unrecognised complication of metabolic syndrome. There are no guidance documents on NAFLD from sub-Saharan Africa, and non-communicable disease (NCD) guidance documents do not include the associated burden of fatty liver disease. Combating the health and socioeconomic burden of NAFLD requires an integrated liver health approach, with task-shifting to primary health care. Using clear guidance documents to link education and management of HIV, viral hepatitis, NAFLD, and associated NCDs is also crucial to an integrated approach to infectious diseases and NCDs, which requires targeted funding from both governments and international development agencies.

撒哈拉以南非洲人口超过 10 亿，承担着全球 24% 的疾病负担，在任何地区的医疗保健方面花费最少，严重依赖国际发展援助提供艾滋病毒、结核病的医疗保健和疟疾。撒哈拉以南非洲发生的人口和流行病学转变，肥胖和糖尿病的患病率不断上升，增加了非酒精性脂肪肝 (NAFLD) 的风险，但这仍然是代谢综合征的一种未被认识的并发症。撒哈拉以南非洲没有关于 NAFLD 的指导文件，非传染性疾病 (NCD) 指导文件不包括脂肪肝疾病的相关负担。对抗 NAFLD 的健康和社会经济负担需要综合肝脏健康方法，随着任务转移到初级卫生保健。使用明确的指导文件将 HIV、病毒性肝炎、NAFLD 和相关非传染性疾病的教育和管理联系起来，对于传染病和非传染性疾病的综合方法也至关重要，这需要政府和国际发展机构提供有针对性的资金。