Abstract

Three new naphthoquinones, 5,6,7-trimethoxydunnione (1), 6,7-dimethoxy-α-dunnione (2), and 5,6,7-trimethoxydunniol (3) were isolated from the tubers of Sinningia mauroana Chautems, together with eleven known compounds: 5-hydroxy-6,7-dimethoxy-α-dunnione (4), 6-hydroxy-7-methoxy-α-dunnione (5), 7-hydroxy-6-methoxy-α-dunnione (6), cedrol (7), tectoquinone (8), plantainoside A (9), calceolarioside A (10), calceolarioside B (11), sanangoside (12), allo-calceolarioside A (13), and conandroside (14). The known compounds 4, 7–9 and 11–13 are being reported for the first time in this species. Hexane, ethyl acetate and ethanol extracts were tested for antioxidant activity by the ORAC-FL method, and the antioxidant capacity was measured as trolox equivalent (TE). The ethyl acetate (8808 µg TE g⁻¹) and ethanol (7911 µg TE g⁻¹) extracts showed high antioxidant capacity, while the hexane extract displayed weak antioxidant capacity (860 µg TE g⁻¹).

摘要

从Sinningia mauroana Chautems的块茎中分离出三种新的萘醌，5,6,7-三甲氧基邓尼酮 ( 1 )、6,7-二甲氧基-α-邓尼酮 ( 2 ) 和 5,6,7-三甲氧基邓尼醇 ( 3 )具有 11 种已知化合物：5-hydroxy-6,7-dimethoxy-α-dunnione ( 4 )、6-hydroxy-7-methoxy-α-dunnione ( 5 )、7-hydroxy-6-methoxy-α-dunnione ( 6 ), 雪松醇 ( 7 ), tectoquinone ( 8 ), plantainoside A ( 9 ), calceolarioside A ( 10 ), calceolarioside B ( 11 ), sanangoside ( 12 ), allo -calceolarioside A (13 ), 和松雄苷 ( 14 )。已知化合物4、7-9和11-13是该物种中的首次报道。采用 ORAC-FL 法测试己烷、乙酸乙酯和乙醇提取物的抗氧化活性，抗氧化能力以 trolox 当量 (TE) 表示。乙酸乙酯（8808 µg TE g ^-1）和乙醇（7911 µg TE g ^-1）提取物显示出高抗氧化能力，而己烷提取物显示出较弱的抗氧化能力（860 µg TE g ^-1）。