Natural Product Research ( IF 2.2 ) Pub Date : 2021-09-09 , DOI: 10.1080/14786419.2021.1956923 Nguyen Thi Thuy Linh 1, 2 , Trinh Thi Thuy 1, 2 , Nguyen Thanh Tam 2 , Ba Thi Cham 1, 2 , Khieu Thi Tam 3 , Nguyen Hoang Sa 4 , Do Thi Thao 5 , Vu Tien Chinh 1, 6 , Nguyen Thi Hoang Anh 1, 2
Abstract
Sixteen compounds (1-16) were isolated from Impatiens chapaensis. Chemical structures were determined by spectroscopic analyses and comparisons with previously published data. This report is the first to identify compounds 1, 5–7, 10, 12–14, and 16 from the genus Impatiens. Seven chosen isolates (5, 7, 10, 11, 12, 15, and 16) were submitted for α-glucosidase inhibition assays with acarbose as the positive control (IC50 = 227.14 ± 13.71 µM). Flavonoid 5 exhibited a significant inhibitory effect (IC50 = 101.00 ± 9.01 µM).
中文翻译:
凤仙花的化学成分。及其α-葡萄糖苷酶抑制活性
摘要
从Impatiens chapaensis中分离出16种化合物( 1-16 ) 。化学结构通过光谱分析和与先前公布的数据进行比较来确定。本报告首次从凤仙花属中鉴定出化合物1、5-7、10、12-14和16。七个选定的分离物(5、7、10、11、12、15和16)提交给α _ _ _以阿卡波糖为阳性对照的葡萄糖苷酶抑制试验 (IC 50 = 227.14 ± 13.71 µM)。类黄酮5表现出显着的抑制作用 (IC 50 = 101.00 ± 9.01 µM)。