Background

Turning is a component of gait that requires planning for movement of multiple body segments and the sophisticated integration of sensory information from the vestibular, visual, and somatosensory systems. These aspects of turning have led to growing interest to quantify turning in clinical populations to characterize deficits or identify disease progression. However, turning may be affected by environmental differences, and the degree to which turning assessments are comparable across research or clinical sites has not yet been evaluated.

Research question

The aim of this study was to determine the extent to which peak turning speeds are equivalent between two sites for a variety of mobility tasks.

Methods

Data were collected at two different sites using separate healthy young adult participants (n = 47 participants total), but recruited using identical inclusion and exclusion criteria. Participants at each site completed three turning tasks: a one-minute walk (1 MW) along a six-meter walkway, a modified Illinois Agility Test (mIAT), and a custom clinical turning course (CCTC). Peak yaw turning speeds were extracted from wearable inertial sensors on the head, trunk, and pelvis. Between-site differences and two one-sided tests (TOST) were used to determine equivalence between sites, based on a minimum effect size reported between individuals with mild traumatic brain injury and healthy control subjects.

Results

No outcomes were different between sites, and equivalence was determined for 6/21 of the outcomes. These findings suggest that some turning tasks and outcome measures may be better suited for multi-site studies. The equivalence results are also dependent on the minimum effect size of interest; nearly all outcomes were equivalent across sites when larger minimum effect sizes of interest were used.

Significance

Together, these results suggest some tasks and outcome measures may be better suited for multi-site studies and literature-based comparisons.

中文翻译：

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使用惯性测量单元评估转弯速度的站点间等效性

背景

转身是步态的一个组成部分，需要规划多个身体部位的运动，并复杂地整合来自前庭、视觉和体感系统的感觉信息。转向的这些方面导致人们越来越有兴趣量化临床人群的转向，以表征缺陷或识别疾病进展。然而，转向可能会受到环境差异的影响，并且尚未评估不同研究或临床地点的转向评估的可比程度。

研究问题

本研究的目的是确定两个站点之间针对各种移动任务的峰值转弯速度的等效程度。

方法

数据是在两个不同地点使用单独的健康年轻成人参与者（总共 n = 47 名参与者）收集的，但使用相同的纳入和排除标准进行招募。每个站点的参与者都完成了三项转弯任务：沿着 6 米长的人行道步行一分钟 (1 MW)、改进的伊利诺伊州敏捷性测试 (mIAT) 和定制的临床转弯课程 (CCTC)。峰值偏航转动速度是从头部、躯干和骨盆上的可穿戴惯性传感器中提取的。基于轻度创伤性脑损伤个体和健康对照受试者之间报告的最小效应大小，使用站点间差异和两个单侧测试 (TOST) 来确定站点之间的等效性。

结果

站点之间没有结果不同，并且确定了 6/21 的结果的等效性。这些发现表明，一些车削任务和结果测量可能更适合多站点研究。等效结果还取决于感兴趣的最小效应大小；当使用更大的感兴趣的最小效应量时，几乎所有的结果在不同地点都是相同的。

意义

总之，这些结果表明一些任务和结果测量可能更适合多站点研究和基于文献的比较。