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Nerve pathology in animal models of neuropathies
Journal of the Peripheral Nervous System ( IF 3.8 ) Pub Date : 2021-09-09 , DOI: 10.1111/jns.12463
Valentina Alda Carozzi 1 , Alessandra Bolino 2 , Maurizio D'Antonio 3 , Angelo Quattrini 4 , Guido Cavaletti 1
Affiliation  

To understand the pathology of axonal degeneration and demyelination in peripheral neuropathy, histological investigations in different animal models that mimic some aspects of human peripheral neuropathy are needed. Thus, in the following section of this special issue, the main pathological features of experimental autoimmune neuritis, animal models of chemotherapy-induced peripheral neuropath and of human inherited peripheral neuropathies (IPNs) will be illustrated. When possible, micrographs from animal models and selected human biopsy will be shown side by side.

中文翻译:

神经病动物模型中的神经病理学

为了了解周围神经病变中轴突变性和脱髓鞘的病理学,需要在模拟人类周围神经病变某些方面的不同动物模型中进行组织学研究。因此,在本期特刊的下一部分中,将说明实验性自身免疫性神经炎、化疗引起的周围神经病变动物模型和人类遗传性周围神经病变 (IPN) 的主要病理特征。如果可能,来自动物模型和选定人体活检的显微照片将并排显示。
更新日期:2021-11-13
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