Journal of Fluorescence ( IF 2.7 ) Pub Date : 2021-09-08 , DOI: 10.1007/s10895-021-02817-x Sha Deng 1 , Qiao Lei 1 , Junzhe Cai 1 , Yuliang Jiang 1 , Jian Shen 1
Although cyanogen ion (CN−) plays important role in industry which also bring acute environmental pollution. More serious, trace CN− enters the human body can cause serious consequences and even death. Therefore, it is of great significance to detect trace CN− with high sensitivity. Herein, a novel aggregation-induced emission (AIE) probe C-BH was synthesized based on coumarin matrix. Probe C-BH showed high selectivity and sensitivity toward CN− by dual channel response due to the excited state intramolecular proton transfer (ESIPT). The low detection limit was calculated to be 0.05 µM. Moreover, probe C-BH was successfully used for imaging CN− in living cells and zebrafish due to its low toxicity and excellent optical properties.
中文翻译:
一种新型聚集诱导发射的香豆素荧光探针检测CN-及其在生物成像中的应用
虽然氰离子(CN -)在工业中发挥着重要作用,但也带来了严重的环境污染。更严重的是,微量CN-进入人体会造成严重后果,甚至死亡。因此,高灵敏度检测痕量CN -具有重要意义。在此,基于香豆素基质合成了一种新型聚集诱导发射(AIE)探针C-BH。由于激发态分子内质子转移 (ESIPT),探针 C-BH 通过双通道响应对 CN -显示出高选择性和灵敏度。低检测限计算为 0.05 µM。此外,探针 C-BH 成功用于 CN 成像-由于其低毒性和优异的光学特性,在活细胞和斑马鱼中。