当前位置: X-MOL 学术Allergy Asthma Clin. Immunol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Exercise induced anaphylaxis in kiwi allergic patient: case report
Allergy, Asthma & Clinical Immunology ( IF 2.7 ) Pub Date : 2021-09-08 , DOI: 10.1186/s13223-021-00595-6
Natalia Ukleja-Sokołowska 1 , Robert Zacniewski 1 , Kinga Lis 1 , Magdalena Żbikowska-Gotz 1 , Andrzej Kuźmiński 1 , Zbigniew Bartuzi 1
Affiliation  

An allergy to kiwi is rare in Poland. Most (65–72%) of the patients who are allergic to kiwi report symptoms of an oral allergy syndrome (OAS); however, systemic manifestations (18–28%) have also been reported. A 27-year-old male patient, previously not suffering from chronic diseases, exercised in the gym. He began with isometric training and then continued with aerobic exercise on a treadmill. After exercise, he ate 2 kiwi (Actinidia deliciosa) fruits. He experienced a swelling of the lips after eating the fruit, followed by an itchy scalp and a swollen face. Approximately 60 min later, the symptoms worsened: the patient suffered from generalized hives, general weakness and a "rumbling" sensation in ears. The patient's condition improved upon the consumption of antihistamines. However, the swelling of the face persisted for 24 h despite previously eating a kiwi without any side effects. By means of diagnostics based on allergen components, an allergy to grass allergen components, especially timothy grass—Phl p 1, Phl p 2 and Phl p 5, was confirmed. The presence of IgE that is specific for Act d 2 kiwi was also found. The patient had an oral food challenge with kiwi fruit at rest and after exercise provocation test. The challenge was negative at rest and positive after exercise. A food-dependent exercise-induced anaphylaxis gathered with a kiwi sensitization was diagnosed. To our knowledge, this case is the first report of a kiwi-allergic patient in whom exercise was a necessary cofactor to induce an anaphylactic reaction.

中文翻译:

猕猴桃过敏患者运动诱发的过敏反应:病例报告

对奇异果过敏在波兰很少见。大多数 (65–72%) 对猕猴桃过敏的患者报告有口腔过敏综合征 (OAS) 的症状;然而,也有全身表现(18-28%)的报道。一名27岁的男性患者,之前没有患慢性病,在健身房锻炼。他从等长训练开始,然后继续在跑步机上进行有氧运动。运动后,他吃了2个奇异果(Actinidia deliciosa)。吃完水果后,他的嘴唇肿胀,随后头皮发痒,脸也肿了。大约 60 分钟后,症状恶化:患者出现全身性荨麻疹、全身无力和耳朵“隆隆”感。服用抗组胺药后,患者的病情有所改善。然而,尽管之前吃过猕猴桃,但面部肿胀持续了 24 小时,没有任何副作用。通过基于过敏原成分的诊断,证实对草过敏原成分过敏,尤其是提摩西草——Phl p 1、Phl p 2和Phl p 5。还发现了 Act d 2 猕猴桃特异的 IgE。患者在休息时和运动激发试验后用猕猴桃进行口服食物激发试验。休息时的挑战为阴性,运动后为阳性。诊断为食物依赖性运动诱发的过敏反应,并伴有猕猴桃致敏。据我们所知,该病例是第一次报告猕猴桃过敏患者,在该患者中,运动是诱发过敏反应的必要辅助因素。证实对草过敏原成分过敏,尤其是蒂莫西草——Phl p 1、Phl p 2 和 Phl p 5。还发现了 Act d 2 猕猴桃特异的 IgE。患者在休息时和运动激发试验后用猕猴桃进行口服食物激发试验。休息时的挑战为阴性,运动后为阳性。诊断为食物依赖性运动诱发的过敏反应,并伴有猕猴桃致敏。据我们所知,该病例是第一次报告猕猴桃过敏患者,在该患者中,运动是诱发过敏反应的必要辅助因素。证实对草过敏原成分过敏,尤其是蒂莫西草——Phl p 1、Phl p 2 和 Phl p 5。还发现了 Act d 2 猕猴桃特异的 IgE。患者在休息时和运动激发试验后用猕猴桃进行口服食物激发试验。休息时的挑战为阴性,运动后为阳性。诊断为食物依赖性运动诱发的过敏反应,并伴有猕猴桃致敏。据我们所知,该病例是第一次报告猕猴桃过敏患者,在该患者中,运动是诱发过敏反应的必要辅助因素。患者在休息时和运动激发试验后用猕猴桃进行口服食物激发试验。休息时的挑战为阴性,运动后为阳性。诊断为食物依赖性运动诱发的过敏反应,并伴有猕猴桃致敏。据我们所知,该病例是第一次报告猕猴桃过敏患者,在该患者中,运动是诱发过敏反应的必要辅助因素。患者在休息时和运动激发试验后用猕猴桃进行口服食物激发试验。休息时的挑战为阴性,运动后为阳性。诊断为食物依赖性运动诱发的过敏反应,并伴有猕猴桃致敏。据我们所知,该病例是第一次报告猕猴桃过敏患者,在该患者中,运动是诱发过敏反应的必要辅助因素。
更新日期:2021-09-08
down
wechat
bug