Atrial fibrillation (AF) is the most common sustained arrhythmia in humans, with an estimated 5.2 million patients in 2010 and a projection of more than 12 million being affected by 2030.¹ The incidence and risk are progressive with age, with a cumulative risk of less than 5% in individuals younger than 55 years, with a lifetime risk of 37% influenced by clinical and genetic factors.² This arrhythmia is a major source of morbidity and mortality worldwide, with a number of clinical risk factors, including hypertension, obesity, diabetes, sleep apnea, and myocardial, valvular, and arrhythmogenic heart diseases.

中文翻译：

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早发性房颤和遗传性心脏病——检测还是不检测？

心房颤动 (AF) 是人类最常见的持续性心律失常，2010 年估计有 520 万患者，预计到 2030^年将有超过 1200 万人受到影响。¹发病率和风险随着年龄的增长而增加，累积风险为在 55 岁以下的个体中低于 5%，受临床和遗传因素影响的终生风险为 37%。²这种心律失常是全世界发病率和死亡率的主要来源，具有许多临床危险因素，包括高血压、肥胖、糖尿病、睡眠呼吸暂停以及心肌、瓣膜和心律失常性心脏病。