Bioadhesives have reached significant milestones over the past two decades. Research has shown not only to produce adhesives capable of adhering to dry tissue but recently wet tissue as well. However, most bioadhesives developed have exhibited high adhesion strength yet lack other properties required for versatility in application, such as elasticity, biocompatibility and biodegradability. Adapting from limitations met from early bioadhesives and meeting the current demand allows novel bioadhesives to reach new milestones for the future. In this review, we overview the progression and variations of bioadhesives, current trends, characterisation techniques and conclude with future perspectives for bioadhesives for tissue engineering applications.

在过去的二十年里，生物粘合剂已经达到了重要的里程碑。研究表明，不仅可以生产能够粘附在干纸巾上的粘合剂，而且最近还可以粘附在湿纸巾上。然而，开发的大多数生物粘合剂都表现出高粘合强度，但缺乏应用中多功能所需的其他特性，例如弹性、生物相容性和生物降解性。适应早期生物粘合剂遇到的局限性并满足当前需求，使新型生物粘合剂能够在未来达到新的里程碑。在这篇综述中，我们概述了生物粘合剂的进展和变化、当前趋势、表征技术，并总结了组织工程应用生物粘合剂的未来前景。