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Application of Reversible Detection Method for N-
Heterocycles ( IF 0.6 ) Pub Date : 2021-09-08 , DOI: 10.3987/com-21-s(r)6
Hiroyuki Konno , Ao Tan , Keigo Takamatsu , Fusheng Xu , Seren Osanai

The first synthesis of the proline-rich cyclic heptapeptide stylissatin B is described. Reversible detection method of N-terminus amino groups using tetrachloro-N-hydroxyphthalimide was applied as the Fmoc-solid phase peptide synthesis. The end points of all reactions of solid support could be pursued by the detection methods.

中文翻译:

N-可逆检测方法的应用

描述了富含脯氨酸的环状七肽 stylissatin B 的首次合成。将使用四氯-N-羟基邻苯二甲酰亚胺的N-末端氨基的可逆检测方法应用于Fmoc-固相肽合成。固体支持物所有反应的终点均可以通过检测方法进行追踪。
更新日期:2021-09-08
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